Her first film in Tamil Arinthum Ariyamalum was popular in Tamil where she starred oppositeNavdeep and Arya. Her next release was Mercury Pookkal opposite Srikanth and Meera Jasmine. She then starred in the film, Manathodu Mazhaikalam, opposite Shaam.
She was also on the show “Zaara Pyaar Ki Saugat” which was airing on the channel Sahara One.
She appeared as a model for universal mobile.
She appeared as a model for many print commercials for reputed brands like Kit-Kat, Monte Carlo, American Express Card, Amway, World Gold Council, Mother Dairy, Havell’s switch and T.V commercial’s like Johnson’s baby prickly heat powder, Hyundai Xing, Sunsilk and Metro tyres, Univercell mobile.Samiksha made her debut in small screen with the T.V soap Zaara where she played the lead role as Sonia Kapoor on Sahara One.
Samiksha was also seen playing the role of Nilanjana Roy in the popular daily soap Yahan Main Ghar Ghar Kheli on Zee TV. She also played the role of the much loved dead wife of the male protogonist ACP Arjun Suryakanth Raute(Shaleen Malhotra), Roshni in Action crime series Arjun (TV series) airing on Star Plus.
Her first Punjabi Movie was ” Lucky Di Unlucky Story ” in 2013 after that ” Jatts in Golmaal ” & ” Kirpaan ” also in 2013.She also appeared in movie ” Fateh ” (2014) opposite ‘ Nav Bajwa’